HIV Target gene Detail Information

> SLC9A3R1 Gene Search Result

Gene Information

Gene Name	SLC9A3R1
Gene ID	9368
Gene Full Name	SLC9A3 regulator 1
Gene Alias	EBP50; NHERF; NHERF1; NHERF-1; NPHLOP2
Transcripts	ENSG00000109062
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Centriolar satellite;Vesicles;
HPA Protein Class Info	Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters
Gene Function	Suppressor gene
Uniport_ID	O14745
HGNC ID	HGNC:11075
VEGA ID	OTTHUMG00000178863
OMIM ID	604990
String ID	9606.ENSP00000262613
PharmGKB ID	PA35931

Target gene [SLC9A3R1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001439	chr17	16	87	62	165	View
4012465	chr17	5			5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SLC9A3R1 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC9A3R1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SLC9A3R1 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC9A3R1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).