HBV Target gene Detail Information

> SLC9A3 Gene Search Result

Gene Information

Gene Name	SLC9A3
Gene ID	6550
Gene Full Name	solute carrier family 9 member A3
Gene Alias	NHE3; DIAR8; NHE-3
Transcripts	ENSG00000281861
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters
Uniport_ID	P48764
HGNC ID	HGNC:11073
VEGA ID	OTTHUMG00000190150
OMIM ID	182307
String ID	9606.ENSP00000264938
Drugbank ID	BE0009845; BE0009757
PharmGKB ID	PA316

Target gene [SLC9A3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1011271	chr5	8	1		9	View
1402948	chr5	8	1		9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SLC9A3 expression and immune infiltrating cell level correlation result in HBV+ samples
SLC9A3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).