HBV Target gene Detail Information

> SLC8A1 Gene Search Result

Gene Information

Gene Name	SLC8A1
Gene ID	6546
Gene Full Name	solute carrier family 8 member A1
Gene Alias	NCX1
Transcripts	ENSG00000183023
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	P32418
HGNC ID	HGNC:11068
VEGA ID	OTTHUMG00000102183
OMIM ID	182305
String ID	9606.ENSP00000384763
Drugbank ID	BE0000986
PharmGKB ID	PA314

Target gene [SLC8A1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1008311	chr2	5	11	5	21	View
1017544	chr2				0	View
1018143	chr2				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SLC8A1 expression and immune infiltrating cell level correlation result in HBV+ samples
SLC8A1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).