HIV Target gene Detail Information

> SLC7A6 Gene Search Result

Gene Information

Gene Name	SLC7A6
Gene ID	9057
Gene Full Name	solute carrier family 7 member 6
Gene Alias	LAT3; LAT-2; y+LAT-2
Transcripts	ENSG00000103064
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q92536
HGNC ID	HGNC:11064
VEGA ID	OTTHUMG00000176544
OMIM ID	605641
String ID	9606.ENSP00000455064
Drugbank ID	BE0010149
PharmGKB ID	PA35924

Target gene [SLC7A6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002768	chr16	61	15	5	81	View
4008230	chr16	15	1		16	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SLC7A6 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC7A6 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SLC7A6 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC7A6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).