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HPV Target gene Detail Information

> SLC6A9 Gene Search Result


Gene Information
Gene Name SLC6A9
Gene ID 6536
Gene Full Name solute carrier family 6 member 9
Gene Alias GLYT1; GCENSG
Transcripts ENSG00000196517
Virus HPV
Gene Type protein coding
HPA Location Info Golgi apparatus;Nucleoplasm;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID P48067
HGNC ID HGNC:11056
VEGA ID OTTHUMG00000008294
OMIM ID 601019
String ID 9606.ENSP00000353791
Drugbank ID BE0000940
PharmGKB ID PA35916
Target gene [SLC6A9] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5300174 chr1 42 22 1 65 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE40774 (GEO) Head and neck squamous cell carcinoma 134 Head and neck Squamous cell carcinomas GLOTTIC LARYNX (EBV-)(2), Head and neck Squamous cell carcinomas HYPOPHARYNX (EBV-)(9), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV-)(23), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV+)(2), Head and neck Squamous cell carcinomas OROPHARYNX (EBV-)(22), Head and neck Squamous cell carcinomas OROPHARYNX (EBV+)(54), Head and neck Squamous cell carcinomas OTHER (EBV+)(1), Head and neck Squamous cell carcinomas SUBGLOTTIC LARYNX (EBV-)(1), Head and neck Squamous cell carcinomas SUPRAGLOTTIC (EBV-)(19), Squamous cell carcinomas SUPRAGLOTTIC (EBV+)(1)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE40774

HeatMap of cell type fractions in all samples Lollipop of SLC6A9 expression and immune infiltrating cell level correlation result in HPV+ samples
SLC6A9 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of SLC6A9 expression and immune infiltrating cell level correlation result in HPV+ samples
SLC6A9 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).