HBV Target gene Detail Information

> SLC6A1 Gene Search Result

Gene Information

Gene Name	SLC6A1
Gene ID	6529
Gene Full Name	solute carrier family 6 member 1
Gene Alias	MAE; GAT1; GABATR; GABATHG
Transcripts	ENSG00000157103
Virus	HBV
Gene Type	protein coding
HPA Location Info	Mitochondria;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters
Uniport_ID	P30531
HGNC ID	HGNC:11042
VEGA ID	OTTHUMG00000044208
OMIM ID	137165
String ID	9606.ENSP00000287766
Drugbank ID	BE0000249
PharmGKB ID	PA309

Target gene [SLC6A1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003441	chr3	127	5	2	134	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SLC6A1 expression and immune infiltrating cell level correlation result in HBV+ samples
SLC6A1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).