HBV Target gene Detail Information

> SLC4A8 Gene Search Result

Gene Information

Gene Name	SLC4A8
Gene ID	9498
Gene Full Name	solute carrier family 4 member 8
Gene Alias	NBC3; NDCBE
Transcripts	ENSG00000050438
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q2Y0W8
HGNC ID	HGNC:11034
VEGA ID	OTTHUMG00000169489
OMIM ID	605024
String ID	9606.ENSP00000405812
Drugbank ID	BE0004680
PharmGKB ID	PA35900

Target gene [SLC4A8] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009634	chr12	11	3	1	15	View
1015456	chr12	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SLC4A8 expression and immune infiltrating cell level correlation result in HBV+ samples
SLC4A8 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).