HIV Target gene Detail Information

> SLC4A7 Gene Search Result

Gene Information

Gene Name	SLC4A7
Gene ID	9497
Gene Full Name	solute carrier family 4 member 7
Gene Alias	NBC2; NBC3; SBC2; NBCN1; SLC4A6
Transcripts	ENSG00000033867
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Cytosol;Focal adhesion sites;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins, Transporters
Uniport_ID	Q9Y6M7
HGNC ID	HGNC:11033
VEGA ID	OTTHUMG00000155679
OMIM ID	603353
String ID	9606.ENSP00000295736
Drugbank ID	BE0004676
PharmGKB ID	PA35899

Target gene [SLC4A7] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002315	chr3	95	3	2	100	View
4003851	chr3	7	13	33	53	View
4004286	chr3	45	1		46	View
4005137	chr3	35			35	View
4009157	chr3	10	2		12	View
4012486	chr3	4	1		5	View
4012815	chr3	3		1	4	View
4013360	chr3		2	1	3	View
4013684	chr3	3			3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SLC4A7 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC4A7 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SLC4A7 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC4A7 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).