HIV Target gene Detail Information

> SLC44A2 Gene Search Result

Gene Information

Gene Name	SLC44A2
Gene ID	57153
Gene Full Name	solute carrier family 44 member 2
Gene Alias	CTL2; PP1292
Transcripts	ENSG00000129353
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cell Junctions;Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q8IWA5
HGNC ID	HGNC:17292
VEGA ID	OTTHUMG00000180585
OMIM ID	606106
String ID	9606.ENSP00000336888
Drugbank ID	BE0002183
PharmGKB ID	PA142670899

Target gene [SLC44A2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001574	chr19	88	27	36	151	View
4014818	chr19	2			2	View
4015076	chr19		1		1	View
4016266	chr19				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SLC44A2 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC44A2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SLC44A2 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC44A2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).