HIV Target gene Detail Information

> SLC39A8 Gene Search Result

Gene Information

Gene Name	SLC39A8
Gene ID	64116
Gene Full Name	solute carrier family 39 member 8
Gene Alias	ZIP8; CDG2N; PP3105; BIGM103; LZT-Hs6
Transcripts	ENSG00000138821
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters
Uniport_ID	Q9C0K1
HGNC ID	HGNC:20862
VEGA ID	OTTHUMG00000131120
OMIM ID	608732
String ID	9606.ENSP00000378310
Drugbank ID	BE0010230; BE0009901
PharmGKB ID	PA134931507

Target gene [SLC39A8] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4010160	chr4	9			9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SLC39A8 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC39A8 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SLC39A8 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC39A8 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).