HIV Target gene Detail Information

> SLC38A1 Gene Search Result

Gene Information

Gene Name	SLC38A1
Gene ID	81539
Gene Full Name	solute carrier family 38 member 1
Gene Alias	ATA1; NAT2; SAT1; SNAT1
Transcripts	ENSG00000111371
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q9H2H9
HGNC ID	HGNC:13447
VEGA ID	OTTHUMG00000169470
OMIM ID	608490
String ID	9606.ENSP00000449756
Drugbank ID	BE0010143; BE0009976
PharmGKB ID	PA37772

Target gene [SLC38A1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001333	chr12	7	163	7	177	View
4003251	chr12	35	12	18	65	View
4004633	chr12	34	5	2	41	View
4006440	chr12	24	1		25	View
4009214	chr12	8	4		12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SLC38A1 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC38A1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SLC38A1 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC38A1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).