HIV Target gene Detail Information

> SLC30A7 Gene Search Result

Gene Information

Gene Name	SLC30A7
Gene ID	148867
Gene Full Name	solute carrier family 30 member 7
Gene Alias	ZNT7; ZnT-7; ZnTL2
Transcripts	ENSG00000162695
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q8NEW0
HGNC ID	HGNC:19306
VEGA ID	OTTHUMG00000011815
OMIM ID	611149
String ID	9606.ENSP00000359130
Drugbank ID	BE0010182
PharmGKB ID	PA134891595

Target gene [SLC30A7] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001647	chr1	7	60	78	145	View
4002546	chr1	7	37	46	90	View
4003033	chr1	61	2	9	72	View
4007540	chr1	11	8		19	View
4012182	chr1			5	5	View
4014300	chr1	2			2	View
4015748	chr1	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SLC30A7 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC30A7 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SLC30A7 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC30A7 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).