HBV Target gene Detail Information

> SLC2A4RG Gene Search Result


Gene Information
Gene Name SLC2A4RG
Gene ID 56731
Gene Full Name SLC2A4 regulator
Gene Alias GEF; HDBP1; HDBP-1; Si-1-2; Si-1-2-19
Transcripts ENSG00000125520
Virus HBV
Gene Type protein coding
HPA Location Info Nuclear speckles;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9NR83
HGNC ID HGNC:15930
VEGA ID OTTHUMG00000032997
OMIM ID 609493
String ID 9606.ENSP00000266077
PharmGKB ID PA38052
Target gene [SLC2A4RG] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000257 chr20 1389 1105 915 3409 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of SLC2A4RG expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
SLC2A4RG expression: Low -> High
Lollipop of SLC2A4RG expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of SLC2A4RG expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SLC2A4RG expression and immune infiltrating cell level correlation result in HBV+ samples
SLC2A4RG expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).