HIV Target gene Detail Information

> SLC2A1 Gene Search Result

Gene Information

Gene Name	SLC2A1
Gene ID	6513
Gene Full Name	solute carrier family 2 member 1
Gene Alias	CSE; PED; DYT9; GLUT; DYT17; DYT18; EIG12; GLUT1; HTLVR; GLUT-1; SDCHCN; GLUT1DS
Transcripts	ENSG00000117394
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	P11166
HGNC ID	HGNC:11005
VEGA ID	OTTHUMG00000007657
OMIM ID	138140
String ID	9606.ENSP00000416293
Drugbank ID	BE0001057
PharmGKB ID	PA35875

Target gene [SLC2A1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001261	chr1	37	63	84	184	View
4001498	chr1	153	3	1	157	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SLC2A1 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC2A1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SLC2A1 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC2A1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).