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HBV Target gene Detail Information

> SLC26A3 Gene Search Result


Gene Information
Gene Name SLC26A3
Gene ID 1811
Gene Full Name solute carrier family 26 member 3
Gene Alias CLD; DRA
Transcripts ENSG00000091138
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters
Uniport_ID P40879
HGNC ID HGNC:3018
VEGA ID OTTHUMG00000154812
OMIM ID 126650
String ID 9606.ENSP00000345873
PharmGKB ID PA35044
Target gene [SLC26A3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002289 chr7 146 132 21 299 View
1002380 chr7 144 119 20 283 View
1002423 chr7 131 126 20 277 View
1002775 chr7 118 73 15 206 View
1403383 chr7 118 73 15 206 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SLC26A3 expression and immune infiltrating cell level correlation result in HBV+ samples
SLC26A3 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).