HPV Target gene Detail Information

> SLC25A2 Gene Search Result


Gene Information
Gene Name SLC25A2
Gene ID 83884
Gene Full Name solute carrier family 25 member 2
Gene Alias ORC2; ORNT2
Transcripts ENSG00000120329
Virus HPV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins, Transporters
Uniport_ID Q9BXI2
HGNC ID HGNC:22921
VEGA ID OTTHUMG00000129604
OMIM ID 608157
String ID 9606.ENSP00000239451
Drugbank ID BE0000258
PharmGKB ID PA134910073
Target gene [SLC25A2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5403107 chr5 6 6 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of SLC25A2 expression and immune infiltrating cell level correlation result in HPV+ samples
SLC25A2 expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of SLC25A2 expression and immune infiltrating cell level correlation result in HPV+ samples
SLC25A2 expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of SLC25A2 expression and immune infiltrating cell level correlation result in HPV+ samples
SLC25A2 expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of SLC25A2 expression and immune infiltrating cell level correlation result in HPV+ samples
SLC25A2 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of SLC25A2 expression and immune infiltrating cell level correlation result in HPV+ samples
SLC25A2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).