HIV Target gene Detail Information

> SLC25A19 Gene Search Result

Gene Information

Gene Name	SLC25A19
Gene ID	60386
Gene Full Name	solute carrier family 25 member 19
Gene Alias	DNC; TPC; MUP1; MCPHA; THMD3; THMD4
Transcripts	ENSG00000125454
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q9HC21
HGNC ID	HGNC:14409
VEGA ID	OTTHUMG00000179607
OMIM ID	606521
String ID	9606.ENSP00000385312
PharmGKB ID	PA37879

Target gene [SLC25A19] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006487	chr17	20	4		24	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SLC25A19 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC25A19 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SLC25A19 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC25A19 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).