HTLV1 Target gene Detail Information

> SLC25A18 Gene Search Result

Gene Information

Gene Name	SLC25A18
Gene ID	83733
Gene Full Name	solute carrier family 25 member 18
Gene Alias	GC2
Transcripts	ENSG00000182902
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Mitochondria;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Plasma proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q9H1K4
HGNC ID	HGNC:10988
VEGA ID	OTTHUMG00000150089
OMIM ID	609303
String ID	9606.ENSP00000329033
Drugbank ID	BE0002275
PharmGKB ID	PA35864

Target gene [SLC25A18] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6022873	chr22	2	2		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of SLC25A18 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLC25A18 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of SLC25A18 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLC25A18 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of SLC25A18 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SLC25A18 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).