HIV Target gene Detail Information

> SLC25A17 Gene Search Result

Gene Information

Gene Name	SLC25A17
Gene ID	10478
Gene Full Name	solute carrier family 25 member 17
Gene Alias	PMP34
Transcripts	ENSG00000100372
Virus	HIV
Gene Type	protein coding
HPA Location Info	Peroxisomes;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	O43808
HGNC ID	HGNC:10987
VEGA ID	OTTHUMG00000151139
OMIM ID	606795
String ID	9606.ENSP00000390722
PharmGKB ID	PA35863

Target gene [SLC25A17] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003064	chr22	57	4	9	70	View
4010593	chr22	5	3		8	View
4010798	chr22	6	2		8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SLC25A17 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC25A17 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SLC25A17 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC25A17 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).