HIV Target gene Detail Information

> SLC25A12 Gene Search Result

Gene Information

Gene Name	SLC25A12
Gene ID	8604
Gene Full Name	solute carrier family 25 member 12
Gene Alias	AGC1; ARALAR; EIEE39
Transcripts	ENSG00000115840
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;Cytosol;
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters
Uniport_ID	O75746
HGNC ID	HGNC:10982
VEGA ID	OTTHUMG00000134290
OMIM ID	603667
String ID	9606.ENSP00000388658
Drugbank ID	BE0000235
PharmGKB ID	PA35858

Target gene [SLC25A12] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4013349	chr2	2	1		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SLC25A12 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC25A12 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SLC25A12 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC25A12 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).