HBV Target gene Detail Information

> SLC1A7 Gene Search Result


Gene Information
Gene Name SLC1A7
Gene ID 6512
Gene Full Name solute carrier family 1 member 7
Gene Alias AAAT; EAAT5
Transcripts ENSG00000162383
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins, Transporters
Uniport_ID O00341
HGNC ID HGNC:10945
VEGA ID OTTHUMG00000008937
OMIM ID 604471
String ID 9606.ENSP00000478639
Drugbank ID BE0002267
PharmGKB ID PA35832
Target gene [SLC1A7] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004129 chr1 29 4 59 92 View
1004505 chr1 34 6 39 79 View
1006740 chr1 34 34 View
1400334 chr1 40 23 57 120 View
1402801 chr1 34 34 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SLC1A7 expression and immune infiltrating cell level correlation result in HBV+ samples
SLC1A7 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).