HIV Target gene Detail Information

> SLC18A1 Gene Search Result

Gene Information

Gene Name	SLC18A1
Gene ID	6570
Gene Full Name	solute carrier family 18 member A1
Gene Alias	CGAT; VAT1; VMAT1
Transcripts	ENSG00000036565
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	FDA approved drug targets, Predicted membrane proteins, Transporters
Uniport_ID	P54219
HGNC ID	HGNC:10934
VEGA ID	OTTHUMG00000097017
OMIM ID	193002
String ID	9606.ENSP00000387549
Drugbank ID	BE0004674
PharmGKB ID	PA324

Target gene [SLC18A1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4013036	chr8	4			4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SLC18A1 expression and immune infiltrating cell level correlation result in HIV+ samples
SLC18A1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).