HBV Target gene Detail Information

> SLC17A5 Gene Search Result


Gene Information
Gene Name SLC17A5
Gene ID 26503
Gene Full Name solute carrier family 17 member 5
Gene Alias SD; AST; NSD; SLD; ISSD; SIASD; SIALIN
Transcripts ENSG00000119899
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Plasma membrane;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Predicted membrane proteins
Uniport_ID Q9NRA2
HGNC ID HGNC:10933
VEGA ID OTTHUMG00000015039
OMIM ID 604322
String ID 9606.ENSP00000348019
PharmGKB ID PA35824
Target gene [SLC17A5] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1010786 chr6 11 11 View
1014946 chr6 1 2 3 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SLC17A5 expression and immune infiltrating cell level correlation result in HBV+ samples
SLC17A5 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).