HBV Target gene Detail Information

> SLC17A4 Gene Search Result


Gene Information
Gene Name SLC17A4
Gene ID 10050
Gene Full Name solute carrier family 17 member 4
Gene Alias KAIA2138
Transcripts ENSG00000146039
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins, Transporters
Uniport_ID Q9Y2C5
HGNC ID HGNC:10932
VEGA ID OTTHUMG00000014410
OMIM ID 604216
String ID 9606.ENSP00000367137
PharmGKB ID PA35823
Target gene [SLC17A4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004910 chr6 49 16 1 66 View
1400287 chr6 1 1 1 3 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SLC17A4 expression and immune infiltrating cell level correlation result in HBV+ samples
SLC17A4 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).