HBV Target gene Detail Information

> SLC12A4 Gene Search Result

Gene Information

Gene Name	SLC12A4
Gene ID	6560
Gene Full Name	solute carrier family 12 member 4
Gene Alias	KCC1; hKCC1; CTC-479C5.17
Transcripts	ENSG00000124067
Virus	HBV
Gene Type	protein coding
HPA Location Info	Endosomes;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	FDA approved drug targets, Predicted membrane proteins, Transporters
Uniport_ID	Q9UP95
HGNC ID	HGNC:10913
VEGA ID	OTTHUMG00000137535
OMIM ID	604119
String ID	9606.ENSP00000395983
Drugbank ID	BE0000601
PharmGKB ID	PA35807

Target gene [SLC12A4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1016846	chr16		1		1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SLC12A4 expression and immune infiltrating cell level correlation result in HBV+ samples
SLC12A4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).