HBV Target gene Detail Information

> SLC12A3 Gene Search Result

Gene Information

Gene Name	SLC12A3
Gene ID	6559
Gene Full Name	solute carrier family 12 member 3
Gene Alias	NCC; TSC; NCCT
Transcripts	ENSG00000070915
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters
Uniport_ID	P55017
HGNC ID	HGNC:10912
VEGA ID	OTTHUMG00000133284
OMIM ID	600968
String ID	9606.ENSP00000402152
Drugbank ID	BE0000419
PharmGKB ID	PA321

Target gene [SLC12A3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1012163	chr16	6	1		7	View
1014470	chr16	2	1		3	View
1401852	chr16	2	1		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SLC12A3 expression and immune infiltrating cell level correlation result in HBV+ samples
SLC12A3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).