HBV Target gene Detail Information

> SLC11A2 Gene Search Result

Gene Information

Gene Name	SLC11A2
Gene ID	4891
Gene Full Name	solute carrier family 11 member 2
Gene Alias	DCT1; DMT1; AHMIO1; NRAMP2
Transcripts	ENSG00000110911
Virus	HBV
Gene Type	protein coding
HPA Location Info	Mitochondria;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	P49281
HGNC ID	HGNC:10908
VEGA ID	OTTHUMG00000169493
OMIM ID	600523
String ID	9606.ENSP00000378364
Drugbank ID	BE0008812; BE0008685
PharmGKB ID	PA259

Target gene [SLC11A2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1019320	chr12				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SLC11A2 expression and immune infiltrating cell level correlation result in HBV+ samples
SLC11A2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).