HBV Target gene Detail Information

> SLC10A1 Gene Search Result

Gene Information

Gene Name	SLC10A1
Gene ID	6554
Gene Full Name	solute carrier family 10 member 1
Gene Alias	NTCP
Transcripts	ENSG00000100652
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins, Transporters
Uniport_ID	Q14973
HGNC ID	HGNC:10905
VEGA ID	OTTHUMG00000171236
OMIM ID	182396
String ID	9606.ENSP00000216540
Drugbank ID	BE0003644
PharmGKB ID	PA317

Target gene [SLC10A1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003479	chr14	99	27	5	131	View
1004073	chr14	61	30	4	95	View
1004427	chr14	75	3	4	82	View
1005927	chr14	32	14		46	View
1006229	chr14	31	10		41	View
1007406	chr14	11	14	2	27	View
1008666	chr14	14	6		20	View
1403384	chr14	11	14	2	27	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SLC10A1 expression and immune infiltrating cell level correlation result in HBV+ samples
SLC10A1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).