HIV Target gene Detail Information

> SLAMF1 Gene Search Result

Gene Information

Gene Name	SLAMF1
Gene ID	6504
Gene Full Name	signaling lymphocytic activation molecule family member 1
Gene Alias	SLAM; CD150; CDw150
Transcripts	ENSG00000117090
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	CD markers, Predicted membrane proteins, Predicted secreted proteins
Uniport_ID	Q13291
HGNC ID	HGNC:10903
VEGA ID	OTTHUMG00000024006
OMIM ID	603492
String ID	9606.ENSP00000306190
PharmGKB ID	PA35803

Target gene [SLAMF1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002151	chr1	31	19	59	109	View
4005596	chr1	27	4		31	View
4010657	chr1	7	1		8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SLAMF1 expression and immune infiltrating cell level correlation result in HIV+ samples
SLAMF1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SLAMF1 expression and immune infiltrating cell level correlation result in HIV+ samples
SLAMF1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).