HIV Target gene Detail Information

> SKIV2L Gene Search Result

Gene Information

Gene Name	SKIV2L
Gene ID	6499
Gene Full Name	Ski2 like RNA helicase
Gene Alias	HLP; 170A; SKI2; DDX13; SKI2W; SKIV2; THES2; SKIV2L1
Transcripts	ENSG00000223493
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;Nucleoplasm;Cytosol;Mitotic spindle;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q15477
HGNC ID	HGNC:10898
VEGA ID	OTTHUMG00000004939
OMIM ID	600478
String ID	9606.ENSP00000364543
PharmGKB ID	PA35798

Target gene [SKIV2L] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003339	chr6	65	6		71	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SKIV2L expression and immune infiltrating cell level correlation result in HIV+ samples
SKIV2L expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SKIV2L expression and immune infiltrating cell level correlation result in HIV+ samples
SKIV2L expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).