HBV Target gene Detail Information

> SKA3 Gene Search Result

Gene Information

Gene Name	SKA3
Gene ID	221150
Gene Full Name	spindle and kinetochore associated complex subunit 3
Gene Alias	RAMA1; C13orf3
Transcripts	ENSG00000165480
Virus	HBV
Gene Type	protein coding
HPA Location Info	Centrosome;Mitotic spindle;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8IX90
HGNC ID	HGNC:20262
VEGA ID	OTTHUMG00000016539
OMIM ID	619247
String ID	9606.ENSP00000319417
PharmGKB ID	PA165505498

Target gene [SKA3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009819	chr13	11	3		14	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SKA3 expression and immune infiltrating cell level correlation result in HBV+ samples
SKA3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).