HIV Target gene Detail Information

> SIRPG Gene Search Result

Gene Information

Gene Name	SIRPG
Gene ID	55423
Gene Full Name	signal regulatory protein gamma
Gene Alias	CD172g; SIRPB2; SIRP-B2; bA77C3.1; SIRPgamma
Transcripts	ENSG00000089012
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	CD markers, Predicted membrane proteins
Uniport_ID	Q9P1W8
HGNC ID	HGNC:15757
VEGA ID	OTTHUMG00000031680
OMIM ID	605466
String ID	9606.ENSP00000305529
PharmGKB ID	PA38034

Target gene [SIRPG] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009467	chr20	3	8		11	View
4011388	chr20	6	1		7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SIRPG expression and immune infiltrating cell level correlation result in HIV+ samples
SIRPG expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SIRPG expression and immune infiltrating cell level correlation result in HIV+ samples
SIRPG expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).