HIV Target gene Detail Information

> SIMC1 Gene Search Result

Gene Information

Gene Name	SIMC1
Gene ID	375484
Gene Full Name	SUMO interacting motifs containing 1
Gene Alias	OOMA1; PLEIAD; C5orf25
Transcripts	ENSG00000170085
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Nucleoli fibrillar center;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8NDZ2
HGNC ID	HGNC:24779
VEGA ID	OTTHUMG00000130663
OMIM ID	618102
String ID	9606.ENSP00000342075
PharmGKB ID	PA144596506

Target gene [SIMC1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4015417	chr5	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SIMC1 expression and immune infiltrating cell level correlation result in HIV+ samples
SIMC1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).