HTLV1 Target gene Detail Information

> SIK2 Gene Search Result

Gene Information

Gene Name	SIK2
Gene ID	23235
Gene Full Name	salt inducible kinase 2
Gene Alias	QIK; SIK-2; SNF1LK2; LOH11CR1I
Transcripts	ENSG00000170145
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Vesicles;Cytosol;Intermediate filaments;Nuclear speckles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Predicted membrane proteins
Uniport_ID	Q9H0K1
HGNC ID	HGNC:21680
VEGA ID	OTTHUMG00000150644
OMIM ID	608973
String ID	9606.ENSP00000305976
Drugbank ID	BE0009492; BE0009538
PharmGKB ID	PA164725750

Target gene [SIK2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6003263	chr11	156	14	1	171	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of SIK2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SIK2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).