HBV Target gene Detail Information

> SHROOM4 Gene Search Result


Gene Information
Gene Name SHROOM4
Gene ID 57477
Gene Full Name shroom family member 4
Gene Alias SHAP; shrm4
Transcripts ENSG00000158352
Virus HBV
Gene Type protein coding
HPA Location Info Focal adhesion sites;Nucleoplasm;Vesicles;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID Q9ULL8
HGNC ID HGNC:29215
VEGA ID OTTHUMG00000021521
OMIM ID 300579
String ID 9606.ENSP00000365188
PharmGKB ID PA147357321
Target gene [SHROOM4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1019374 chrX 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SHROOM4 expression and immune infiltrating cell level correlation result in HBV+ samples
SHROOM4 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).