HBV Target gene Detail Information

> SHROOM3 Gene Search Result

Gene Information

Gene Name	SHROOM3
Gene ID	57619
Gene Full Name	shroom family member 3
Gene Alias	SHRM; APXL3; ShrmL; MSTP013
Transcripts	ENSG00000138771
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q8TF72
HGNC ID	HGNC:30422
VEGA ID	OTTHUMG00000157075
OMIM ID	604570
String ID	9606.ENSP00000296043
PharmGKB ID	PA147357295

Target gene [SHROOM3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1000748	chr4	706	406	568	1680	View
1001618	chr4	419	92	63	574	View
1004641	chr4	40	16	18	74	View
1006367	chr4	38	1		39	View
1008426	chr4	21			21	View
1010041	chr4	10	3		13	View
1011341	chr4	7	1	1	9	View
1015517	chr4	2			2	View
1017519	chr4				0	View
1402384	chr4	10	3		13	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SHROOM3 expression and immune infiltrating cell level correlation result in HBV+ samples
SHROOM3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).