HIV Target gene Detail Information

> SHPRH Gene Search Result

Gene Information

Gene Name	SHPRH
Gene ID	257218
Gene Full Name	SNF2 histone linker PHD RING helicase
Gene Alias	bA545I5.2
Transcripts	ENSG00000146414
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nuclear membrane;Nucleoplasm;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q149N8
HGNC ID	HGNC:19336
VEGA ID	OTTHUMG00000015750
OMIM ID	608048
String ID	9606.ENSP00000356475
PharmGKB ID	PA134880315

Target gene [SHPRH] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009976	chr6	9		1	10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SHPRH expression and immune infiltrating cell level correlation result in HIV+ samples
SHPRH expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SHPRH expression and immune infiltrating cell level correlation result in HIV+ samples
SHPRH expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).