HBV Target gene Detail Information

> SHE Gene Search Result

Gene Information

Gene Name	SHE
Gene ID	126669
Gene Full Name	Src homology 2 domain containing E
Transcripts	ENSG00000169291
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	Q5VZ18
HGNC ID	HGNC:27004
VEGA ID	OTTHUMG00000036072
OMIM ID	610482
String ID	9606.ENSP00000307369
PharmGKB ID	PA142670919

Target gene [SHE] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1011107	chr1	10			10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SHE expression and immune infiltrating cell level correlation result in HBV+ samples
SHE expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).