HBV Target gene Detail Information

> SHC4 Gene Search Result

Gene Information

Gene Name	SHC4
Gene ID	399694
Gene Full Name	SHC adaptor protein 4
Gene Alias	RaLP; SHCD
Transcripts	ENSG00000185634
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Predicted intracellular proteins, RAS pathway related proteins
Uniport_ID	Q6S5L8
HGNC ID	HGNC:16743
VEGA ID	OTTHUMG00000131513
OMIM ID	617372
String ID	9606.ENSP00000329668
PharmGKB ID	PA142670917

Target gene [SHC4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1002952	chr15	105	44	36	185	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SHC4 expression and immune infiltrating cell level correlation result in HBV+ samples
SHC4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).