HIV Target gene Detail Information

> SH3PXD2A Gene Search Result

Gene Information

Gene Name	SH3PXD2A
Gene ID	9644
Gene Full Name	SH3 and PX domains 2A
Gene Alias	FISH; TKS5; SH3MD1
Transcripts	ENSG00000107957
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q5TCZ1
HGNC ID	HGNC:23664
VEGA ID	OTTHUMG00000018997
String ID	9606.ENSP00000348215
PharmGKB ID	PA134956816

Target gene [SH3PXD2A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000925	chr10	90	38	136	264	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SH3PXD2A expression and immune infiltrating cell level correlation result in HIV+ samples
SH3PXD2A expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SH3PXD2A expression and immune infiltrating cell level correlation result in HIV+ samples
SH3PXD2A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).