HIV Target gene Detail Information

> SH3KBP1 Gene Search Result


Gene Information
Gene Name SH3KBP1
Gene ID 30011
Gene Full Name SH3 domain containing kinase binding protein 1
Gene Alias HSB1; CIN85; GIG10; HSB-1; MIG18; CD2BP3
Transcripts ENSG00000147010
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q96B97
HGNC ID HGNC:13867
VEGA ID OTTHUMG00000021227
OMIM ID 300374
String ID 9606.ENSP00000380921
PharmGKB ID PA37822
Target gene [SH3KBP1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4002999 chrX 44 12 16 72 View
4003741 chrX 5 6 44 55 View
4005891 chrX 16 8 5 29 View
4008988 chrX 10 3 13 View
4009352 chrX 12 12 View
4011410 chrX 7 7 View
4011640 chrX 3 3 6 View
4013363 chrX 2 1 3 View
4013939 chrX 3 3 View
4014574 chrX 1 1 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of SH3KBP1 expression and immune infiltrating cell level correlation result in HIV+ samples
SH3KBP1 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of SH3KBP1 expression and immune infiltrating cell level correlation result in HIV+ samples
SH3KBP1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).