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HBV Target gene Detail Information

> SH3BP4 Gene Search Result


Gene Information
Gene Name SH3BP4
Gene ID 23677
Gene Full Name SH3 domain binding protein 4
Gene Alias TTP; BOG25
Transcripts ENSG00000130147
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9P0V3
HGNC ID HGNC:10826
VEGA ID OTTHUMG00000133292
OMIM ID 605611
String ID 9606.ENSP00000386862
PharmGKB ID PA35734
Target gene [SH3BP4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003141 chr2 106 26 30 162 View
1004666 chr2 69 4 73 View
1400460 chr2 10 10 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of SH3BP4 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
SH3BP4 expression: Low -> High
Lollipop of SH3BP4 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of SH3BP4 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SH3BP4 expression and immune infiltrating cell level correlation result in HBV+ samples
SH3BP4 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).