HBV Target gene Detail Information

> SH2D4A Gene Search Result

Gene Information

Gene Name	SH2D4A
Gene ID	63898
Gene Full Name	SH2 domain containing 4A
Gene Alias	SH2A; PPP1R38
Transcripts	ENSG00000104611
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9H788
HGNC ID	HGNC:26102
VEGA ID	OTTHUMG00000097005
OMIM ID	614968
String ID	9606.ENSP00000265807
PharmGKB ID	PA134891945

Target gene [SH2D4A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1000244	chr8	2004	1143	410	3557	View
1005322	chr8	53	3		56	View
1402146	chr8	53	3		56	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SH2D4A expression and immune infiltrating cell level correlation result in HBV+ samples
SH2D4A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).