HIV Target gene Detail Information

> SH2D3A Gene Search Result

Gene Information

Gene Name	SH2D3A
Gene ID	10045
Gene Full Name	SH2 domain containing 3A
Gene Alias	NSP1
Transcripts	ENSG00000125731
Virus	HIV
Gene Type	protein coding
HPA Location Info	Microtubules;Cytokinetic bridge;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9BRG2
HGNC ID	HGNC:16885
VEGA ID	OTTHUMG00000181868
OMIM ID	604721
String ID	9606.ENSP00000245908
PharmGKB ID	PA38192

Target gene [SH2D3A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4013640	chr19	2	1		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SH2D3A expression and immune infiltrating cell level correlation result in HIV+ samples
SH2D3A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).