HIV Target gene Detail Information

> SGSM3 Gene Search Result

Gene Information

Gene Name	SGSM3
Gene ID	27352
Gene Full Name	small G protein signaling modulator 3
Gene Alias	MAP; CIP85; RUSC3; RUTBC3; RABGAP5; RabGAP-5; rabGAPLP
Transcripts	ENSG00000100359
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q96HU1
HGNC ID	HGNC:25228
VEGA ID	OTTHUMG00000151141
OMIM ID	610440
String ID	9606.ENSP00000248929
PharmGKB ID	PA162403194

Target gene [SGSM3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000131	chr22	788	105	57	950	View
4012408	chr22	2	3		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of SGSM3 expression and immune infiltrating cell level correlation result in HIV+ samples
SGSM3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of SGSM3 expression and immune infiltrating cell level correlation result in HIV+ samples
SGSM3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).