HBV Target gene Detail Information

> SGCZ Gene Search Result


Gene Information
Gene Name SGCZ
Gene ID 137868
Gene Full Name sarcoglycan zeta
Gene Alias ZSG1
Transcripts ENSG00000185053
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins
Uniport_ID Q96LD1
HGNC ID HGNC:14075
VEGA ID OTTHUMG00000090827
OMIM ID 608113
String ID 9606.ENSP00000371512
PharmGKB ID PA38378
Target gene [SGCZ] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007051 chr8 9 22 31 View
1012798 chr8 6 6 View
1012799 chr8 6 6 View
1013652 chr8 3 1 4 View
1019363 chr8 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SGCZ expression and immune infiltrating cell level correlation result in HBV+ samples
SGCZ expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).