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HBV Target gene Detail Information

> SFXN5 Gene Search Result


Gene Information
Gene Name SFXN5
Gene ID 94097
Gene Full Name sideroflexin 5
Gene Alias BBG-TCC; SLC56A5
Transcripts ENSG00000144040
Virus HBV
Gene Type protein coding
HPA Location Info Mitochondria;Nucleoplasm;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q8TD22
HGNC ID HGNC:16073
VEGA ID OTTHUMG00000129775
OMIM ID 615572
String ID 9606.ENSP00000272433
PharmGKB ID PA38088
Target gene [SFXN5] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000671 chr2 82 884 665 1631 View
1000828 chr2 99 815 463 1377 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of SFXN5 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
SFXN5 expression: Low -> High
Lollipop of SFXN5 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of SFXN5 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SFXN5 expression and immune infiltrating cell level correlation result in HBV+ samples
SFXN5 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).