HTLV1 Target gene Detail Information

> SFXN4 Gene Search Result


Gene Information
Gene Name SFXN4
Gene ID 119559
Gene Full Name sideroflexin 4
Gene Alias BCRM1; COXPD18; SLC56A4
Transcripts ENSG00000183605
Virus HTLV1
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID Q6P4A7
HGNC ID HGNC:16088
VEGA ID OTTHUMG00000019147
OMIM ID 615564
String ID 9606.ENSP00000347924
PharmGKB ID PA38093
Target gene [SFXN4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6005583 chr10 70 9 5 84 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of SFXN4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SFXN4 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of SFXN4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SFXN4 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of SFXN4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
SFXN4 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).