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HBV Target gene Detail Information

> SFMBT2 Gene Search Result


Gene Information
Gene Name SFMBT2
Gene ID 57713
Gene Full Name Scm like with four mbt domains 2
Transcripts ENSG00000198879
Virus HBV
Gene Type protein coding
HPA Location Info Nuclear speckles;Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q5VUG0
HGNC ID HGNC:20256
VEGA ID OTTHUMG00000017630
OMIM ID 615392
String ID 9606.ENSP00000380353
PharmGKB ID PA134866013
Target gene [SFMBT2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006300 chr10 36 3 1 40 View
1006301 chr10 36 3 1 40 View
1006329 chr10 36 3 1 40 View
1009731 chr10 14 14 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of SFMBT2 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
SFMBT2 expression: Low -> High
Lollipop of SFMBT2 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of SFMBT2 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of SFMBT2 expression and immune infiltrating cell level correlation result in HBV+ samples
SFMBT2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).