HBV Target gene Detail Information

> SF3B1 Gene Search Result

Gene Information

Gene Name	SF3B1
Gene ID	23451
Gene Full Name	splicing factor 3b subunit 1
Gene Alias	MDS; PRP10; Hsh155; PRPF10; SAP155; SF3b155
Transcripts	ENSG00000115524
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	O75533
HGNC ID	HGNC:10768
VEGA ID	OTTHUMG00000154447
OMIM ID	605590
String ID	9606.ENSP00000335321
Drugbank ID	BE0009319
PharmGKB ID	PA35686

Target gene [SF3B1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1010058	chr2	12	1		13	View
1400811	chr2	12	1		13	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of SF3B1 expression and immune infiltrating cell level correlation result in HBV+ samples
SF3B1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).